Vous êtes ici : Accueil > Actualités > traitement par PPC et enzyme du foie

traitement par PPC et enzyme du foie

un aperçu des articles récents liés au sommeil, parus ou en instance de parution, référencés sur Pubmed.
Vous en trouverez les résumés ci-dessous.

-La revue Lung publie un article traitant du bénéfice entraîné par le dépistage et le traitement des apnées du sommeil par pression positive continue sur les patients souffrant de stéatose hépatique non alcoolique.

-La revue Sleep Medecine souligne la prégnance de la consommation nocturne de tabac chez les patients souffrant d’un syndrome des jambes sans repos, phénomènes associés le plus souvent à des troubles de la nutrition.

- Le British Journal of anaesthesia s’attarde sur les difficultés rencontrées par les médecins anesthésistes lors d’interventions en mode ambulatoire sur des patients obèses du fait de la prévalence de troubles respiratoires du sommeil (SAOS) et de diabète dans cette population.


-----

Lung. 2010 Jan 12. [Epub ahead of print]

Continuous Positive Airway Pressure Improves Sleep Apnea Associated Fatty Liver.

Shpirer I, Copel L, Broide E, Elizur A.

Institute of Pulmonary Medicine, Assaf Harofeh Medical Center, Zerifin, Israel.

Treatment of sleep apnea can improve liver enzyme abnormalities in patients with nonalcoholic fatty liver disease. However, the effect of continuous positive airway pressure therapy for sleep apnea on liver fat accumulation was not assessed. Liver biopsy is the "gold standard" for determining and quantifying liver fat accumulation; however, obtaining two separate liver biopsies is challenging. We examined, using a newly described computerized tomography method to quantify liver fat accumulation, whether treatment of sleep apnea improves liver steatosis. In a prospective cohort study, patients diagnosed with obstructive sleep apnea, at Assaf Harofeh Medical Center's sleep laboratory, were identified. Patients completed a questionnaire and underwent blood tests for liver enzymes and lipid profile, and computed tomography scans to determine the liver attenuation index. Patients with liver attenuation index </=-10 (correlating with histological macrovesicular steatosis >/=30%) were treated with continuous positive airway pressure for 2-3 years. Subsequently, patients underwent repeat blood tests and tomography scans. Of 47 patients who were analyzed, 16 had a low liver attenuation index (</=-10). Patients with moderate-severe sleep apnea had worse liver attenuation index compared with patients with mild sleep apnea despite comparable body mass index and triglycerides levels. Patients who were compliant with 2-3 years of continuous positive airway pressure treatment demonstrated significant improvement in the mean liver attenuation index, whereas noncompliant patients did not. Patients with nonalcoholic fatty-liver disease may benefit from identification and treatment for obstructive sleep apnea because treatment may improve liver steatosis.

------

Sleep Med. 2010 Jan 9. [Epub ahead of print]

Increased prevalence of nocturnal smoking in restless legs syndrome (RLS).

Provini F, Antelmi E, Vignatelli L, Zaniboni A, Naldi G, Calandra-Buonaura G, Vetrugno R, Plazzi G, Pizza F, Montagna P.

Department of Neurological Sciences, University of Bologna, Bologna, Italy.

OBJECTIVE: We investigated the prevalence of nocturnal smoking (NS) in patients with RLS. METHODS: One hundred RLS patients living in Emilia-Romagna (Northern Italy) and 100 matched controls, randomly selected from the general population, underwent interviews for the presence of nocturnal smoking and for obsessive-compulsive traits, depression, excessive daytime sleepiness (EDS) and subjective sleep quality. RESULTS: NS was more prevalent in RLS patients than controls (lifetime prevalence: 12% vs. 2%, P=0.012). Patients with NS had more frequently Sleep-Related Eating Disorders (SRED) than patients without NS (83.3% vs. 26.1%, P=0.0002). Pathological and borderline Maudsley Obsessive-Compulsive Inventory (MOCI) values as well as pathological values at the Beck Depression Inventory (BDI) increased from controls to RLS patients without NS to RLS patients with NS (P=0.005 and P=0.01, respectively). CONCLUSIONS: We demonstrate an increased prevalence of NS in patients with RLS, in many cases associated with increased SRED. NS may be associated with psychopathological traits in RLS and may be relevant in the management of RLS patients. Copyright © 2009 Elsevier B.V. All rights reserved.

-----

British Journal of Anaesthesia. 2009 Dec;103 Suppl 1:i23-30.

Obesity, obstructive sleep apnoea, and diabetes mellitus: anaesthetic implications.

Candiotti K, Sharma S, Shankar R.

 

Department of Anesthesiology, Pain Management and Perioperative Medicine, University of Miami, Miller School of Medicine, PO Box 016370 (R-370), Miami, FL 33136, USA. kcandiot@med.miami.edu

Obesity is an epidemic in much of the Western World. The extent of this problem, combined with the increasing preference for ambulatory surgical procedures, has produced a difficult situation for many anaesthesiologists. Even the simplest anaesthetic procedures can become very complicated and potentially difficult in this population. Although there are numerous complications associated with obesity, perhaps obstructive sleep apnoea (OSA) and diabetes mellitus are among the more significant. Patients with OSA are often not ideal candidates for certain day-case procedures, but many outpatient procedures can be performed on patients with OSA as long as attention is paid to anaesthetic technique. Diabetic patients are prone to numerous complications in the perioperative period, including cardiac problems, but with careful management, they are able to undergo day-case surgical procedures safely.

Tél : 01 42 66 45 85

du Lundi au Vendredi

de 9h à 19h

72 boulevard de Courcelles

75017 PARIS

Métro Courcelles

Recherche sur le site


Groupe Santé Sommeil

Le groupe médical Santé Sommeil a pour vocation de diagnostiquer et traiter les troubles du sommeil et de la veille chez l’adulte et l’enfant.